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Rapid and efficient syntheses of tryptophans using a continuous-flow quaternization-substitution reaction of gramines with a chiral nucleophilic glycine equivalent.
Koiwa, Daichi; Ohira, Masayuki; Hiramatsu, Takahiro; Abe, Hidenori; Kawamoto, Tetsuji; Ishihara, Yuji; Ignacio, Bernardo; Mansour, Noel; Romoff, Todd.
Affiliation
  • Koiwa D; Research & Development Division, Hamari Chemicals, Ltd, 1-19-40, Nankokita, Suminoe-ku, Osaka, 559-0034, Japan. tetsuji-kawamoto@hamari.co.jp.
  • Ohira M; Research & Development Division, Hamari Chemicals, Ltd, 1-19-40, Nankokita, Suminoe-ku, Osaka, 559-0034, Japan. tetsuji-kawamoto@hamari.co.jp.
  • Hiramatsu T; Research & Development Division, Hamari Chemicals, Ltd, 1-19-40, Nankokita, Suminoe-ku, Osaka, 559-0034, Japan. tetsuji-kawamoto@hamari.co.jp.
  • Abe H; Research & Development Division, Hamari Chemicals, Ltd, 1-19-40, Nankokita, Suminoe-ku, Osaka, 559-0034, Japan. tetsuji-kawamoto@hamari.co.jp.
  • Kawamoto T; Research & Development Division, Hamari Chemicals, Ltd, 1-19-40, Nankokita, Suminoe-ku, Osaka, 559-0034, Japan. tetsuji-kawamoto@hamari.co.jp.
  • Ishihara Y; Research & Development Division, Hamari Chemicals, Ltd, 1-19-40, Nankokita, Suminoe-ku, Osaka, 559-0034, Japan. tetsuji-kawamoto@hamari.co.jp.
  • Ignacio B; Hamari Chemicals USA, Inc., 11558 Sorrento Valley Rd Suite 3, San Diego, California, 92121, USA.
  • Mansour N; Hamari Chemicals USA, Inc., 11558 Sorrento Valley Rd Suite 3, San Diego, California, 92121, USA.
  • Romoff T; Hamari Chemicals USA, Inc., 11558 Sorrento Valley Rd Suite 3, San Diego, California, 92121, USA.
Org Biomol Chem ; 20(42): 8331-8340, 2022 Nov 02.
Article in En | MEDLINE | ID: mdl-36250233
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tryptophan / Glycine Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2022 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tryptophan / Glycine Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2022 Document type: Article Affiliation country: