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Design, synthesis, molecular modeling, and bioactivity evaluation of 1,10-phenanthroline and prodigiosin (Ps) derivatives and their Copper(I) complexes against mTOR and HDAC enzymes as highly potent and effective new anticancer therapeutic drugs.
Cetin, M Mustafa; Peng, Wenjing; Unruh, Daniel; Mayer, Michael F; Mechref, Yehia; Yelekci, Kemal.
Affiliation
  • Cetin MM; Department of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Kadir Has University, Istanbul, Turkey.
  • Peng W; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, United States.
  • Unruh D; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, United States.
  • Mayer MF; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, United States.
  • Mechref Y; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, United States.
  • Yelekci K; Department of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Kadir Has University, Istanbul, Turkey.
Front Pharmacol ; 13: 980479, 2022.
Article in En | MEDLINE | ID: mdl-36267272
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Front Pharmacol Year: 2022 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Front Pharmacol Year: 2022 Document type: Article Affiliation country: Country of publication: