Contemporary Epidemiology of Primary Biliary Cholangitis.
Clin Liver Dis
; 26(4): 555-570, 2022 11.
Article
in En
| MEDLINE
| ID: mdl-36270716
ABSTRACT
Primary biliary cholangitis (PBC) is a cholestatic liver disease with potential evolution to liver cirrhosis when left untreated. Despite being rare, PBC has a substantial impact on the quality of life and survival of affected patients. Women are the most diagnosed worldwide; however, male subjects seem to have more aggressive disease and worse prognosis. Changing epidemiologic trends are emerging in PBC, with increasing global prevalence and slight smoothing of sex differences. In this review we present available data on incidence rates and prevalence of PBC worldwide, highlighting geographic differences and factors impacting clinical outcomes.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cholangitis
/
Liver Cirrhosis, Biliary
Type of study:
Diagnostic_studies
/
Incidence_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Aspects:
Patient_preference
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
Clin Liver Dis
Journal subject:
GASTROENTEROLOGIA
Year:
2022
Document type:
Article
Affiliation country: