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Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease.
Huang, Boshi; Ghatge, Mohini S; Donkor, Akua K; Musayev, Faik N; Deshpande, Tanvi M; Al-Awadh, Mohammed; Alhashimi, Rana T; Zhu, Hongmei; Omar, Abdelsattar M; Telen, Marilyn J; Zhang, Yan; McMahon, Tim J; Abdulmalik, Osheiza; Safo, Martin K.
Affiliation
  • Huang B; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Ghatge MS; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Donkor AK; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Musayev FN; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Deshpande TM; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Al-Awadh M; Vertex Pharmaceutical Incorporated, Boston, MA 02210, USA.
  • Alhashimi RT; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Zhu H; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Omar AM; Department of Medicine, Duke University Health System, Durham NC 27710, USA.
  • Telen MJ; Department of Medicine, Durham VA Health Care System, Durham NC 27705, USA.
  • Zhang Y; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Alsulaymanyah, Jeddah 21589, Saudi Arabia.
  • McMahon TJ; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.
  • Abdulmalik O; Department of Medicine, Duke University Health System, Durham NC 27710, USA.
  • Safo MK; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
Molecules ; 27(20)2022 Oct 12.
Article in En | MEDLINE | ID: mdl-36296435
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemoglobin, Sickle / Anemia, Sickle Cell Limits: Animals Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemoglobin, Sickle / Anemia, Sickle Cell Limits: Animals Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2022 Document type: Article Affiliation country: Country of publication: