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Site-specific CRISPR-based mitochondrial DNA manipulation is limited by gRNA import.
Schmiderer, Ludwig; Yudovich, David; Oburoglu, Leal; Hjort, Martin; Larsson, Jonas.
Affiliation
  • Schmiderer L; Division of Molecular Medicine and Gene Therapy, Department of Laboratory Medicine and Lund Stem Cell Center, Lund University, 221 00, Lund, Sweden. ludwig.schmiderer@med.lu.se.
  • Yudovich D; BMC A12, Lund University, 221 84, Lund, Sweden. ludwig.schmiderer@med.lu.se.
  • Oburoglu L; Division of Molecular Medicine and Gene Therapy, Department of Laboratory Medicine and Lund Stem Cell Center, Lund University, 221 00, Lund, Sweden.
  • Hjort M; Division of Molecular Medicine and Gene Therapy, Department of Laboratory Medicine and Lund Stem Cell Center, Lund University, 221 00, Lund, Sweden.
  • Larsson J; Chemical Biology and Therapeutics, Department of Experimental Medical Science, Lund University, 221 00, Lund, Sweden.
Sci Rep ; 12(1): 18687, 2022 11 04.
Article in En | MEDLINE | ID: mdl-36333335
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Mitochondrial / RNA, Guide, Kinetoplastida Limits: Humans Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Mitochondrial / RNA, Guide, Kinetoplastida Limits: Humans Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Country of publication: