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Unscheduled DNA replication in G1 causes genome instability and damage signatures indicative of replication collisions.
Reusswig, Karl-Uwe; Bittmann, Julia; Peritore, Martina; Courtes, Mathilde; Pardo, Benjamin; Wierer, Michael; Mann, Matthias; Pfander, Boris.
Affiliation
  • Reusswig KU; DNA Replication and Genome Integrity, Max Planck Institute of Biochemistry, 82152, Martinsried, Germany.
  • Bittmann J; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA.
  • Peritore M; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Courtes M; DNA Replication and Genome Integrity, Max Planck Institute of Biochemistry, 82152, Martinsried, Germany.
  • Pardo B; DNA Replication and Genome Integrity, Max Planck Institute of Biochemistry, 82152, Martinsried, Germany.
  • Wierer M; Genome Maintenance Mechanisms in Health and Disease, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147, Cologne, Germany.
  • Mann M; Institut de Génétique Humaine (IGH), Université de Montpellier - Centre National de la Recherche Scientifique, 34396, Montpellier, France.
  • Pfander B; Institut de Génétique Humaine (IGH), Université de Montpellier - Centre National de la Recherche Scientifique, 34396, Montpellier, France.
Nat Commun ; 13(1): 7014, 2022 11 18.
Article in En | MEDLINE | ID: mdl-36400763
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genomic Instability / DNA Repair Type of study: Etiology_studies / Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genomic Instability / DNA Repair Type of study: Etiology_studies / Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Country of publication: