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Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation.
Aoki, Yusuke; Han, Qinghong; Tome, Yasunori; Yamamoto, Jun; Kubota, Yutaro; Masaki, Noriyuki; Obara, Koya; Hamada, Kazuyuki; Wang, Justin D; Inubushi, Sachiko; Bouvet, Michael; Clarke, Steven G; Nishida, Kotaro; Hoffman, Robert M.
Affiliation
  • Aoki Y; AntiCancer Inc, San Diego, CA, United States.
  • Han Q; Department of Surgery, University of California San Diego, La Jolla, CA, United States.
  • Tome Y; Department of Orthopedic Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara, Japan.
  • Yamamoto J; AntiCancer Inc, San Diego, CA, United States.
  • Kubota Y; Department of Orthopedic Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara, Japan.
  • Masaki N; AntiCancer Inc, San Diego, CA, United States.
  • Obara K; Department of Surgery, University of California San Diego, La Jolla, CA, United States.
  • Hamada K; AntiCancer Inc, San Diego, CA, United States.
  • Wang JD; Department of Surgery, University of California San Diego, La Jolla, CA, United States.
  • Inubushi S; AntiCancer Inc, San Diego, CA, United States.
  • Bouvet M; Department of Surgery, University of California San Diego, La Jolla, CA, United States.
  • Clarke SG; AntiCancer Inc, San Diego, CA, United States.
  • Nishida K; Department of Surgery, University of California San Diego, La Jolla, CA, United States.
  • Hoffman RM; AntiCancer Inc, San Diego, CA, United States.
Front Oncol ; 12: 1009548, 2022.
Article in En | MEDLINE | ID: mdl-36408173
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Front Oncol Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Front Oncol Year: 2022 Document type: Article Affiliation country: Country of publication: