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Loss-of-function lesions impact B-cell development and fitness but are insufficient to drive CLL in mouse models.
ten Hacken, Elisa; Yin, Shanye; Redd, Robert; Hernández Sánchez, María; Clement, Kendell; Hoffmann, Gabriela Brunsting; Regis, Fara F; Witten, Elizabeth; Li, Shuqiang; Neuberg, Donna; Pinello, Luca; Livak, Kenneth J; Wu, Catherine J.
Affiliation
  • ten Hacken E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Yin S; Harvard Medical School, Boston, MA.
  • Redd R; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Hernández Sánchez M; Harvard Medical School, Boston, MA.
  • Clement K; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA.
  • Hoffmann GB; The Institute of Cancer Molecular and Cellular Biology-Cancer Research Center, Instituto de Investigación Biomédica de Salamanca, University of Salamanca, Salamanca, Spain.
  • Regis FF; Departament of Biochemistry and Molecular Biology, Pharmacy School, Universidad Complutense de Madrid, Madrid, Spain.
  • Witten E; Center for Cancer Research, and Center for Computational and Integrative Biology, Molecular Pathology Unit, Massachussetts General Hospital, Boston, MA.
  • Li S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Neuberg D; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Pinello L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Livak KJ; Translational Immunogenomics Lab, Dana-Farber Cancer Institute, Boston, MA.
  • Wu CJ; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.
Blood Adv ; 7(16): 4514-4517, 2023 08 22.
Article in En | MEDLINE | ID: mdl-36477552
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell Limits: Animals Language: En Journal: Blood Adv Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell Limits: Animals Language: En Journal: Blood Adv Year: 2023 Document type: Article Affiliation country: Country of publication: