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R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response.
Crossley, Magdalena P; Song, Chenlin; Bocek, Michael J; Choi, Jun-Hyuk; Kousouros, Joseph N; Sathirachinda, Ataya; Lin, Cindy; Brickner, Joshua R; Bai, Gongshi; Lans, Hannes; Vermeulen, Wim; Abu-Remaileh, Monther; Cimprich, Karlene A.
Affiliation
  • Crossley MP; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
  • Song C; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
  • Bocek MJ; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
  • Choi JH; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
  • Kousouros JN; Biometrology Group, Division of Chemical and Biological Metrology, Korea Research Institute of Standards and Science, Daejeon, South Korea.
  • Sathirachinda A; Department of Bio-Analytical Science, University of Science & Technology, Daejeon, South Korea.
  • Lin C; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
  • Brickner JR; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
  • Bai G; Department of Chemical Engineering, Stanford University, Stanford, CA, USA.
  • Lans H; Department of Genetics, Stanford University, Stanford, CA, USA.
  • Vermeulen W; The Institute for Chemistry, Engineering & Medicine for Human Health (ChEM-H), Stanford University, Stanford, CA, USA.
  • Abu-Remaileh M; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
  • Cimprich KA; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
Nature ; 613(7942): 187-194, 2023 01.
Article in En | MEDLINE | ID: mdl-36544021
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / RNA / Cytoplasm / R-Loop Structures / Innate Immunity Recognition / Nucleic Acid Heteroduplexes Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / RNA / Cytoplasm / R-Loop Structures / Innate Immunity Recognition / Nucleic Acid Heteroduplexes Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2023 Document type: Article Affiliation country: Country of publication: