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Modified Primary Anastomosis Using an Intestinal Internal Drainage Tube for Crohn's Disease: A Pilot Study.
Deng, Aojian; Zheng, Shaopeng; Yuan, Lianwen; Xiang, Kaimin; Wang, Fen.
Affiliation
  • Deng A; Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha 410013, China.
  • Zheng S; Hunan Key Laboratory of Non-Resolving Inflammation and Cancer, Changsha 410013, China.
  • Yuan L; Department of Gastroenterology, Zhongshan Hospital, Xiamen University, Xiamen 361005, China.
  • Xiang K; Department of Geriatric Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China.
  • Wang F; Department of Gastroenterological Surgery, The Third Xiangya Hospital, Central South University, Changsha 410013, China.
J Clin Med ; 12(1)2023 Jan 03.
Article in En | MEDLINE | ID: mdl-36615164
PURPOSE: Surgical treatment is an important part of the management of Crohn's disease (CD). However, the current recommended staged procedures require two operations, with long hospital stays and high costs, while traditional primary anastomosis has a high risk of complications. Therefore, the aim of this study was to compare the clinical efficacy and safety of modified primary anastomosis using intestinal internal drainage tubes for CD. METHODS: In this study, emergency and nonemergency CD patients were included separately. Then, the patients were divided into three subgroups: patients with intestinal internal drainage tubes (modified primary anastomosis), staged procedures, and traditional primary anastomosis. The main outcomes were the number of hospitalizations, length and cost of the first hospital stay, length and cost of total hospital stays, and complications. RESULTS: The outcomes of the three subgroups of emergency CD patients were not significantly different. For nonemergency CD patients, patients with intestinal internal drainage tubes had shorter total hospital stays and fewer hospitalizations compared with the staged procedures subgroup, while no significant differences in any outcomes were observed between the modified and traditional primary anastomosis subgroups. CONCLUSIONS: For emergency CD patients, no significant advantage in terms of the main outcomes was observed for modified primary anastomosis. For nonemergency CD patients, modified primary anastomosis reduced the length of total hospital stays and hospitalizations compared with staged procedures. The placement of intestinal internal drainage tubes allows some patients who cannot undergo primary anastomosis to undergo it, which is a modification of traditional primary anastomosis.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Clin Med Year: 2023 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Clin Med Year: 2023 Document type: Article Affiliation country: Country of publication: