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The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9.
Bayly-Jones, Charles; Ho, Bill H T; Lau, Corinna; Leung, Eleanor W W; D'Andrea, Laura; Lupton, Christopher J; Ekkel, Susan M; Venugopal, Hariprasad; Whisstock, James C; Mollnes, Tom E; Spicer, Bradley A; Dunstone, Michelle A.
Affiliation
  • Bayly-Jones C; Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.
  • Ho BHT; ARC Centre of Excellence in Advanced Molecular Imaging, Monash University, Melbourne, Australia.
  • Lau C; Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.
  • Leung EWW; Research laboratory, Nordland Hospital Trust, Bodø, Norway.
  • D'Andrea L; Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.
  • Lupton CJ; Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.
  • Ekkel SM; Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.
  • Venugopal H; Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.
  • Whisstock JC; Ramaciotti Centre for Cryo-Electron Microscopy, Monash University, Clayton, 3800, VIC, Australia.
  • Mollnes TE; Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.
  • Spicer BA; ARC Centre of Excellence in Advanced Molecular Imaging, Monash University, Melbourne, Australia.
  • Dunstone MA; EMBL Australia, Monash University, Melbourne, VIC, 3800, Australia.
Commun Biol ; 6(1): 42, 2023 01 13.
Article in En | MEDLINE | ID: mdl-36639734
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Complement C9 / Complement Membrane Attack Complex Limits: Animals / Humans Language: En Journal: Commun Biol Year: 2023 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Complement C9 / Complement Membrane Attack Complex Limits: Animals / Humans Language: En Journal: Commun Biol Year: 2023 Document type: Article Affiliation country: