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Mechanistic model of MAPK signaling reveals how allostery and rewiring contribute to drug resistance.
Fröhlich, Fabian; Gerosa, Luca; Muhlich, Jeremy; Sorger, Peter K.
Affiliation
  • Fröhlich F; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
  • Gerosa L; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
  • Muhlich J; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
  • Sorger PK; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
Mol Syst Biol ; 19(2): e10988, 2023 02 10.
Article in En | MEDLINE | ID: mdl-36700386
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins B-raf / Melanoma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Syst Biol Journal subject: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Year: 2023 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins B-raf / Melanoma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Syst Biol Journal subject: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Year: 2023 Document type: Article Affiliation country: