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Increased versus conventional adalimumab dose interval for patients with Crohn's disease in stable remission (LADI): a pragmatic, open-label, non-inferiority, randomised controlled trial.
van Linschoten, Reinier C A; Jansen, Fenna M; Pauwels, Renske W M; Smits, Lisa J T; Atsma, Femke; Kievit, Wietske; de Jong, Dirk J; de Vries, Annemarie C; Boekema, Paul J; West, Rachel L; Bodelier, Alexander G L; Gisbertz, Ingrid A M; Wolfhagen, Frank H J; Römkens, Tessa E H; Lutgens, Maurice W M D; van Bodegraven, Adriaan A; Oldenburg, Bas; Pierik, Marieke J; Russel, Maurice G V M; de Boer, Nanne K; Mallant-Hent, Rosalie C; Ter Borg, Pieter C J; van der Meulen-de Jong, Andrea E; Jansen, Jeroen M; Jansen, Sita V; Tan, Adrianus C I T L; van der Woude, C Janneke; Hoentjen, Frank.
Affiliation
  • van Linschoten RCA; Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, Netherlands; Department of Gastroenterology and Hepatology, Franciscus Gasthuis and Vlietland, Rotterdam, Netherlands.
  • Jansen FM; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, Netherlands.
  • Pauwels RWM; Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, Netherlands.
  • Smits LJT; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, Netherlands.
  • Atsma F; Radboud Institute for Health Sciences, Scientific Center for Quality of Healthcare, Radboud University Medical Center, Nijmegen, Netherlands.
  • Kievit W; Radboud institute for Health Science, Department for Health Evidence, Radboud University Medical Center, Nijmegen, Netherlands.
  • de Jong DJ; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, Netherlands.
  • de Vries AC; Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, Netherlands.
  • Boekema PJ; Department of Gastroenterology and Hepatology, Maxima Medical Center, Eindhoven, Netherlands.
  • West RL; Department of Gastroenterology and Hepatology, Franciscus Gasthuis and Vlietland, Rotterdam, Netherlands.
  • Bodelier AGL; Department of Gastroenterology and Hepatology, Amphia Hospital, Breda, Netherlands.
  • Gisbertz IAM; Department of Gastroenterology and Hepatology, Bernhoven Hospital, Uden, Netherlands.
  • Wolfhagen FHJ; Department of Gastroenterology and Hepatology, Albert Schweitzer Hospital, Dordrecht, Netherlands.
  • Römkens TEH; Department of Gastroenterology and Hepatology, Jeroen Bosch Hospital, 's-Hertogenbosch, Netherlands.
  • Lutgens MWMD; Department of Gastroenterology and Hepatology, Elisabeth Twee Steden Ziekenhuis, Tilburg, Netherlands.
  • van Bodegraven AA; Department of Gastroenterology, Geriatrics, Internal and Intensive Care Medicine (Co-MIK), Zuyderland Medical Center, Sittard-Geleen/Heerlen, Netherlands.
  • Oldenburg B; Department of Gastroenterology and Hepatology, UMC Utrecht, Utrecht, Netherlands.
  • Pierik MJ; Department of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, Netherlands.
  • Russel MGVM; Department of Gastroenterology and Hepatology, Medisch Spectrum Twente, Twente, Netherlands.
  • de Boer NK; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam University Medical Centre, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Mallant-Hent RC; Department of Gastroenterology and Hepatology, Flevoziekenhuis, Almere, Netherlands.
  • Ter Borg PCJ; Department of Gastroenterology and Hepatology, Ikazia Hospital, Rotterdam, Netherlands.
  • van der Meulen-de Jong AE; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands.
  • Jansen JM; Department of Gastroenterology and Hepatology, OLVG, Amsterdam, Netherlands.
  • Jansen SV; Department of Gastroenterology and Hepatology, Reinier de Graaf Gasthuis, Delft, Netherlands.
  • Tan ACITL; Department of Gastroenterology and Hepatology, CWZ Hospital, Nijmegen, Netherlands.
  • van der Woude CJ; Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, Netherlands.
  • Hoentjen F; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, Netherlands; Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, AB, Canada. Electronic address: hoentjen@ualberta.ca.
Lancet Gastroenterol Hepatol ; 8(4): 343-355, 2023 04.
Article in En | MEDLINE | ID: mdl-36736339

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Crohn Disease Type of study: Clinical_trials / Guideline Limits: Adolescent / Adult / Female / Humans / Male Country/Region as subject: Europa Language: En Journal: Lancet Gastroenterol Hepatol Year: 2023 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Crohn Disease Type of study: Clinical_trials / Guideline Limits: Adolescent / Adult / Female / Humans / Male Country/Region as subject: Europa Language: En Journal: Lancet Gastroenterol Hepatol Year: 2023 Document type: Article Affiliation country: