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Characterization of high-molecular weight by-products in the production of a trivalent bispecific 2+1 heterodimeric antibody.
Cramer, Dario A T; Franc, Vojtech; Heidenreich, Anna-Katharina; Hook, Michaela; Adibzadeh, Mahdi; Reusch, Dietmar; Heck, Albert J R; Haberger, Markus.
Affiliation
  • Cramer DAT; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands.
  • Franc V; Netherlands Proteomics Center, Utrecht, The Netherlands.
  • Heidenreich AK; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands.
  • Hook M; Netherlands Proteomics Center, Utrecht, The Netherlands.
  • Adibzadeh M; Pharma Technical Development, Roche Diagnostics GmbH, Penzberg, Germany.
  • Reusch D; Pharma Technical Development, Roche Diagnostics GmbH, Penzberg, Germany.
  • Heck AJR; Pharma Technical Development, F. Hoffmann-La Roche AG, Basel, Switzerland.
  • Haberger M; Pharma Technical Development, Roche Diagnostics GmbH, Penzberg, Germany.
MAbs ; 15(1): 2175312, 2023.
Article in En | MEDLINE | ID: mdl-36799476
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antibodies, Bispecific Limits: Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antibodies, Bispecific Limits: Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Document type: Article Affiliation country: Country of publication: