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MET exon 14 skipping mutation is a hepatocyte growth factor (HGF)-dependent oncogenic driver in vitro and in humanised HGF knock-in mice.
Fernandes, Marie; Hoggard, Brynna; Jamme, Philippe; Paget, Sonia; Truong, Marie-José; Grégoire, Valérie; Vinchent, Audrey; Descarpentries, Clotilde; Morabito, Angela; Stanislovas, Justas; Farage, Enoir; Meneboo, Jean-Pascal; Sebda, Shéhérazade; Bouchekioua-Bouzaghou, Katia; Nollet, Marie; Humez, Sarah; Perera, Timothy; Fromme, Paul; Grumolato, Luca; Figeac, Martin; Copin, Marie-Christine; Tulasne, David; Cortot, Alexis B; Kermorgant, Stéphanie; Kherrouche, Zoulika.
Affiliation
  • Fernandes M; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, France.
  • Hoggard B; Barts Cancer Institute, Queen Mary University of London, UK.
  • Jamme P; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, France.
  • Paget S; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, France.
  • Truong MJ; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, France.
  • Grégoire V; Univ Lille, Department of Pathology, CHU Lille, France.
  • Vinchent A; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, France.
  • Descarpentries C; Univ. Lille, Molecular Biology, Hormonology Metabolism Nutrition Oncology, CHU Lille, France.
  • Morabito A; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, France.
  • Stanislovas J; Barts Cancer Institute, Queen Mary University of London, UK.
  • Farage E; Barts Cancer Institute, Queen Mary University of London, UK.
  • Meneboo JP; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, Lille, France.
  • Sebda S; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, Lille, France.
  • Bouchekioua-Bouzaghou K; Barts Cancer Institute, Queen Mary University of London, UK.
  • Nollet M; Barts Cancer Institute, Queen Mary University of London, UK.
  • Humez S; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, France.
  • Perera T; Univ Lille, Department of Pathology, CHU Lille, France.
  • Fromme P; OCTIMET Oncology NV, Beerse, Belgium.
  • Grumolato L; Department of Mechanical Engineering, University College London, UK.
  • Figeac M; Univ Rouen Normandie, Inserm, NorDiC UMR 1239, 76000 Rouen, France.
  • Copin MC; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, Lille, France.
  • Tulasne D; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, France.
  • Cortot AB; Univ Lille, Department of Pathology, CHU Lille, France.
  • Kermorgant S; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, France.
  • Kherrouche Z; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, France.
Mol Oncol ; 17(11): 2257-2274, 2023 Nov.
Article in En | MEDLINE | ID: mdl-36799689

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Oncol Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2023 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Oncol Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2023 Document type: Article Affiliation country: Country of publication: