Bacterial acetate metabolism and its influence on human epithelia.
Emerg Top Life Sci
; 8(1): 1-13, 2024 Feb 22.
Article
in En
| MEDLINE
| ID: mdl-36945843
ABSTRACT
Short-chain fatty acids are known modulators of host-microbe interactions and can affect human health, inflammation, and outcomes of microbial infections. Acetate is the most abundant but least well-studied of these modulators, with most studies focusing on propionate and butyrate, which are considered to be more potent. In this mini-review, we summarize current knowledge of acetate as an important anti-inflammatory modulator of interactions between hosts and microorganisms. This includes a summary of the pathways by which acetate is metabolized by bacteria and human cells, the functions of acetate in bacterial cells, and the impact that microbially derived acetate has on human immune function.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Propionates
/
Fatty Acids, Volatile
Limits:
Humans
Language:
En
Journal:
Emerg Top Life Sci
Year:
2024
Document type:
Article
Affiliation country:
Country of publication:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM