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Nano-Hybrid Ag@LCCs Systems with Potential Wound-Healing Properties.
Corsaro, Carmelo; Condorelli, Marcello; Speciale, Antonio; Cimino, Francesco; Forte, Giuseppe; Barreca, Francesco; Spadaro, Salvatore; Muscarà, Claudia; D'Arrigo, Manuela; Toscano, Giovanni; D'Urso, Luisa; Compagnini, Giuseppe; Neri, Fortunato; Saija, Antonina; Fazio, Enza.
Affiliation
  • Corsaro C; Department of Mathematical and Computational Sciences, Physics Science and Earth Science, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • Condorelli M; Department of Chemical Sciences, University of Catania, V.le A. Doria 6, I-95125 Catania, Italy.
  • Speciale A; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • Cimino F; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • Forte G; Department of Chemical Sciences, University of Catania, V.le A. Doria 6, I-95125 Catania, Italy.
  • Barreca F; Department of Mathematical and Computational Sciences, Physics Science and Earth Science, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • Spadaro S; Department of Mathematical and Computational Sciences, Physics Science and Earth Science, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • Muscarà C; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • D'Arrigo M; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • Toscano G; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • D'Urso L; Department of Chemical Sciences, University of Catania, V.le A. Doria 6, I-95125 Catania, Italy.
  • Compagnini G; Department of Chemical Sciences, University of Catania, V.le A. Doria 6, I-95125 Catania, Italy.
  • Neri F; Department of Mathematical and Computational Sciences, Physics Science and Earth Science, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • Saija A; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
  • Fazio E; Department of Mathematical and Computational Sciences, Physics Science and Earth Science, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
Materials (Basel) ; 16(6)2023 Mar 18.
Article in En | MEDLINE | ID: mdl-36984315
ABSTRACT
The synthesis of contaminant-free silver@linear carbon chains (Ag@LCCs) nanohybrid systems, at different Ag/LCCs ratios, by pulsed laser ablation was studied. The ablation products were first characterized by several diagnostic techniques conventional UV-Vis optical absorption and micro-Raman spectroscopies, as well as scanning electron microscopy, operating in transmission mode. The experimental evidence was confirmed by the theoretical simulations' data. Furthermore, to gain a deeper insight into the factors influencing metal@LCCs biological responses in relation to their physical properties, in this work, we investigated the bioproperties of the Ag@LCCs nanosystems towards a wound-healing activity. We found that Ag@LCC nanohybrids maintain good antibacterial properties and possess a better capability, in comparison with Ag NPs, of interacting with mammalian cells, allowing us to hypothesize that mainly the Ag@LCCs 31 might be suitable for topical application in wound healing, independent of (or in addition to) the antibacterial effect.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Materials (Basel) Year: 2023 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Materials (Basel) Year: 2023 Document type: Article Affiliation country: