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Preclinical characterization and IND-enabling safety studies for PNT001, an antibody that recognizes cis-pT231 tau.
Foster, Kelly; Manca, Matteo; McClure, Kim; Koivula, Pyry; Trojanowski, John Q; Havas, Daniel; Chancellor, Sarah; Goldstein, Lee; Brunden, Kurt R; Kraus, Allison; Ahlijanian, Michael K.
Affiliation
  • Foster K; Pinteon Therapeutics, Inc., Discovery Biology, Newton, Massachusetts, USA.
  • Manca M; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • McClure K; Pinteon Therapeutics, Inc., Discovery Biology, Newton, Massachusetts, USA.
  • Koivula P; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Trojanowski JQ; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Havas D; Psychogenics, Inc, Biology Paramus, New Jersey, USA.
  • Chancellor S; Molecular Aging & Development Laboratory, Boston University School of Medicine, USA.
  • Goldstein L; Molecular Aging & Development Laboratory, Boston University School of Medicine, USA.
  • Brunden KR; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Kraus A; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Ahlijanian MK; Pinteon Therapeutics, Inc., Discovery Biology, Newton, Massachusetts, USA.
Alzheimers Dement ; 19(10): 4662-4674, 2023 10.
Article in En | MEDLINE | ID: mdl-37002928
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Tauopathies Limits: Animals / Humans Language: En Journal: Alzheimers Dement Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Tauopathies Limits: Animals / Humans Language: En Journal: Alzheimers Dement Year: 2023 Document type: Article Affiliation country: Country of publication: