Front propagation in the shadow wave-pinning model.
J Math Biol
; 86(5): 72, 2023 Apr 10.
Article
in En
| MEDLINE
| ID: mdl-37037923
In this paper we consider a non-local bistable reaction-diffusion equation which is a simplified version of the wave-pinning model of cell polarization. In the small diffusion limit, a typical solution u(x, t) of this model approaches one of the stable states of the bistable nonlinearity in different parts of the spatial domain [Formula: see text], separated by an interface moving at a normal velocity regulated by the integral [Formula: see text]. In what is often referred to as wave-pinning, feedback between mass-conservation and bistablity causes the interface to slow and approach a fixed limit. In the limit of a small diffusivity [Formula: see text], we prove that for any [Formula: see text] the interface can be estimated within [Formula: see text] of the location as predicted using formal asymptotics. We also discuss the sharpness of our result by comparing the formal asymptotic results with numerical simulations.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Prognostic_studies
Language:
En
Journal:
J Math Biol
Year:
2023
Document type:
Article
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