Your browser doesn't support javascript.
loading
Front propagation in the shadow wave-pinning model.
Gomez, Daniel; Lam, King-Yeung; Mori, Yoichiro.
Affiliation
  • Gomez D; Department of Mathematics, University of Pennsylvania, Philadelphia, PA, 19104-6395, USA. d1gomez@sas.upenn.edu.
  • Lam KY; Department of Mathematics, The Ohio State University, Columbus, OH, 43210-1174, USA.
  • Mori Y; Department of Mathematics, University of Pennsylvania, Philadelphia, PA, 19104-6395, USA.
J Math Biol ; 86(5): 72, 2023 Apr 10.
Article in En | MEDLINE | ID: mdl-37037923
In this paper we consider a non-local bistable reaction-diffusion equation which is a simplified version of the wave-pinning model of cell polarization. In the small diffusion limit, a typical solution u(x, t) of this model approaches one of the stable states of the bistable nonlinearity in different parts of the spatial domain [Formula: see text], separated by an interface moving at a normal velocity regulated by the integral [Formula: see text]. In what is often referred to as wave-pinning, feedback between mass-conservation and bistablity causes the interface to slow and approach a fixed limit. In the limit of a small diffusivity [Formula: see text], we prove that for any [Formula: see text] the interface can be estimated within [Formula: see text] of the location as predicted using formal asymptotics. We also discuss the sharpness of our result by comparing the formal asymptotic results with numerical simulations.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: J Math Biol Year: 2023 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: J Math Biol Year: 2023 Document type: Article Affiliation country: Country of publication: