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A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang, Na; Occean, James R; Melters, Daniël P; Shi, Changyou; Wang, Lin; Stransky, Stephanie; Doyle, Maire E; Cui, Chang-Yi; Delannoy, Michael; Fan, Jinshui; Slama, Eliza; Egan, Josephine M; De, Supriyo; Cunningham, Steven C; de Cabo, Rafael; Sidoli, Simone; Dalal, Yamini; Sen, Payel.
Affiliation
  • Yang N; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Occean JR; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Melters DP; Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, NIH, Bethesda, MD 21224, USA.
  • Shi C; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Wang L; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Stransky S; Department of Biochemistry, Albert Einstein School of Medicine, Bronx, NY 10461, USA.
  • Doyle ME; Laboratory of Clinical Investigation, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Cui CY; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Delannoy M; JHU SOM Microscope Facility, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Fan J; Computational Biology and Genomics Core, Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Slama E; Department of Surgery, Ascension Saint Agnes Hospital, Baltimore, MD 21229, USA.
  • Egan JM; Laboratory of Clinical Investigation, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • De S; Computational Biology and Genomics Core, Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Cunningham SC; Department of Surgery, Ascension Saint Agnes Hospital, Baltimore, MD 21229, USA.
  • de Cabo R; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
  • Sidoli S; Department of Biochemistry, Albert Einstein School of Medicine, Bronx, NY 10461, USA.
  • Dalal Y; Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, NIH, Bethesda, MD 21224, USA.
  • Sen P; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD 21224, USA. Electronic address: payel.sen@nih.gov.
Mol Cell ; 83(10): 1659-1676.e11, 2023 05 18.
Article in En | MEDLINE | ID: mdl-37116496
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Histones Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Histones Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2023 Document type: Article Affiliation country: Country of publication: