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A prime editor mouse to model a broad spectrum of somatic mutations in vivo.
Ely, Zackery A; Mathey-Andrews, Nicolas; Naranjo, Santiago; Gould, Samuel I; Mercer, Kim L; Newby, Gregory A; Cabana, Christina M; Rideout, William M; Jaramillo, Grissel Cervantes; Khirallah, Jennifer M; Holland, Katie; Randolph, Peyton B; Freed-Pastor, William A; Davis, Jessie R; Kulstad, Zachary; Westcott, Peter M K; Lin, Lin; Anzalone, Andrew V; Horton, Brendan L; Pattada, Nimisha B; Shanahan, Sean-Luc; Ye, Zhongfeng; Spranger, Stefani; Xu, Qiaobing; Sánchez-Rivera, Francisco J; Liu, David R; Jacks, Tyler.
Affiliation
  • Ely ZA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Mathey-Andrews N; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Naranjo S; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Gould SI; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Mercer KL; Harvard Medical School, Boston, MA, USA.
  • Newby GA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Cabana CM; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Rideout WM; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Jaramillo GC; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Khirallah JM; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Holland K; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Randolph PB; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Freed-Pastor WA; Howard Hughes Medical Institute, Harvard University, Cambridge, MA, USA.
  • Davis JR; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Kulstad Z; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Westcott PMK; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Lin L; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Anzalone AV; Harvard-MIT Division of Health Sciences and Technology, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Horton BL; Department of Biomedical Engineering, Tufts University, Medford, MA, USA.
  • Pattada NB; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Shanahan SL; Department of Biology, Angelo State University, San Angelo, TX, USA.
  • Ye Z; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Spranger S; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Xu Q; Howard Hughes Medical Institute, Harvard University, Cambridge, MA, USA.
  • Sánchez-Rivera FJ; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Liu DR; Harvard Medical School, Boston, MA, USA.
  • Jacks T; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Nat Biotechnol ; 42(3): 424-436, 2024 Mar.
Article in En | MEDLINE | ID: mdl-37169967
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / RNA, Guide, CRISPR-Cas Systems Limits: Animals / Humans Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2024 Document type: Article Affiliation country:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / RNA, Guide, CRISPR-Cas Systems Limits: Animals / Humans Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2024 Document type: Article Affiliation country: