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FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation.
Fujinuma, Shun; Nakatsumi, Hirokazu; Shimizu, Hideyuki; Sugiyama, Shigeaki; Harada, Akihito; Goya, Takeshi; Tanaka, Masatake; Kohjima, Motoyuki; Takahashi, Masatomo; Izumi, Yoshihiro; Yagi, Mikako; Kang, Dongchon; Kaneko, Mari; Shigeta, Mayo; Bamba, Takeshi; Ohkawa, Yasuyuki; Nakayama, Keiichi I.
Affiliation
  • Fujinuma S; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Nakatsumi H; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Shimizu H; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Sugiyama S; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Harada A; Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Goya T; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Tanaka M; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Kohjima M; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Takahashi M; Division of Metabolomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Izumi Y; Division of Metabolomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Yagi M; Department of Clinical Chemistry and Laboratory Medicine, Kyushu University, Fukuoka, Japan; Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Kang D; Department of Clinical Chemistry and Laboratory Medicine, Kyushu University, Fukuoka, Japan.
  • Kaneko M; Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
  • Shigeta M; Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
  • Bamba T; Division of Metabolomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Ohkawa Y; Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Nakayama KI; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan. Electronic address: nakayak1@bioreg.kyushu-u.ac.jp.
Cell Rep ; 42(5): 112530, 2023 05 30.
Article in En | MEDLINE | ID: mdl-37209098
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Non-alcoholic Fatty Liver Disease / Liver Neoplasms Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Rep Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Non-alcoholic Fatty Liver Disease / Liver Neoplasms Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Rep Year: 2023 Document type: Article Affiliation country: Country of publication: