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Accelerating clinical development of a live attenuated vaccine against Salmonella Paratyphi A (VASP): study protocol for an observer-participant-blind randomised control trial of a novel oral vaccine using a human challenge model of Salmonella Paratyphi A infection in healthy adult volunteers.
McCann, Naina; Emary, Katherine; Singh, Nisha; Mclean, Florence; Camara, Susana; Jones, Elizabeth; Kim, Young Chan; Liu, Xinxue; Greenland, Melanie; Conlin, Kerry; Hill, Jennifer; Verheul, Marije; Robinson, Hannah; Angus, Brian; Ramasamy, Maheshi N; Levine, Myron M; Pollard, Andrew J.
Affiliation
  • McCann N; Department of Paediatrics, Oxford Vaccine Group, University of Oxford, Oxford, UK naina.mccann@paediatrics.ox.ac.uk.
  • Emary K; NIHR Oxford Biomedical Research Centre, Oxford, UK.
  • Singh N; Department of Paediatrics, Oxford Vaccine Group, University of Oxford, Oxford, UK.
  • Mclean F; NIHR Oxford Biomedical Research Centre, Oxford, UK.
  • Camara S; Department of Paediatrics, Oxford Vaccine Group, University of Oxford, Oxford, UK.
  • Jones E; NIHR Oxford Biomedical Research Centre, Oxford, UK.
  • Kim YC; Department of Paediatrics, Oxford Vaccine Group, University of Oxford, Oxford, UK.
  • Liu X; NIHR Oxford Biomedical Research Centre, Oxford, UK.
  • Greenland M; Department of Paediatrics, Oxford Vaccine Group, University of Oxford, Oxford, UK.
  • Conlin K; NIHR Oxford Biomedical Research Centre, Oxford, UK.
  • Hill J; Department of Paediatrics, Oxford Vaccine Group, University of Oxford, Oxford, UK.
  • Verheul M; NIHR Oxford Biomedical Research Centre, Oxford, UK.
  • Robinson H; Department of Paediatrics, Oxford Vaccine Group, University of Oxford, Oxford, UK.
  • Angus B; NIHR Oxford Biomedical Research Centre, Oxford, UK.
  • Ramasamy MN; Department of Paediatrics, Oxford Vaccine Group, University of Oxford, Oxford, UK.
  • Levine MM; NIHR Oxford Biomedical Research Centre, Oxford, UK.
  • Pollard AJ; Department of Paediatrics, Oxford Vaccine Group, University of Oxford, Oxford, UK.
BMJ Open ; 13(5): e068966, 2023 05 24.
Article in En | MEDLINE | ID: mdl-37225278

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Salmonella paratyphi A / Cardiovascular Diseases Type of study: Clinical_trials / Guideline / Prognostic_studies Aspects: Ethics Limits: Adult / Humans Language: En Journal: BMJ Open Year: 2023 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Salmonella paratyphi A / Cardiovascular Diseases Type of study: Clinical_trials / Guideline / Prognostic_studies Aspects: Ethics Limits: Adult / Humans Language: En Journal: BMJ Open Year: 2023 Document type: Article Affiliation country: Country of publication: