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Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models.
Zhou, Sujin; Lin, Yan; Zhao, Zhenggang; Lai, Yunhao; Lu, Mengmeng; Shao, Zishen; Mo, Xinyu; Mu, Yunping; Liang, Zhipeng; Wang, Xinxing; Qu, Jingming; Shen, Hua; Li, Fanghong; Zhao, Allan Z.
Affiliation
  • Zhou S; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong Province, China.
  • Lin Y; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong Province, China; The Laboratory Center for Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu Province, China.
  • Zhao Z; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong Province, China.
  • Lai Y; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong Province, China.
  • Lu M; Guangzhou Sinogen Pharmaceutical Co., Ltd., Guangzhou, Guangdong Province, China.
  • Shao Z; Guangzhou Sinogen Pharmaceutical Co., Ltd., Guangzhou, Guangdong Province, China.
  • Mo X; Guangzhou Sinogen Pharmaceutical Co., Ltd., Guangzhou, Guangdong Province, China.
  • Mu Y; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong Province, China.
  • Liang Z; Department of Radiology, Sir Ruan-Ruan Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, China.
  • Wang X; Department of Oncology, Sir Ruan-Ruan Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, China.
  • Qu J; Department of Thoracic and Heart Surgery, Xuzhou Cancer Hospital, Jiangsu University, Xuzhou, Jiangsu Province, China.
  • Shen H; Department of Oncology, Sir Ruan-Ruan Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, China.
  • Li F; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong Province, China. Electronic address: fli@gdut.edu.cn.
  • Zhao AZ; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong Province, China. Electronic address: azzhao@gdut.edu.cn.
Cell Rep Med ; 4(6): 101070, 2023 06 20.
Article in En | MEDLINE | ID: mdl-37269826
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Methionine / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Rep Med Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Methionine / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Rep Med Year: 2023 Document type: Article Affiliation country: Country of publication: