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Synthesis of Imidazole-Based Molecules under Ultrasonic Irradiation Approaches.
Yu, Xian-Long; Fan, Yu-Han; Zheng, Xu-Nan; Gao, Jing-Fei; Zhuang, Li-Geng; Yu, Yang-Ling; Xi, Jing-Hui; Zhang, Da-Wei.
Affiliation
  • Yu XL; College of Chemistry, Jilin University, Changchun 130012, China.
  • Fan YH; College of Plant Science, Jilin University, Changchun 130062, China.
  • Zheng XN; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
  • Gao JF; College of Plant Science, Jilin University, Changchun 130062, China.
  • Zhuang LG; College of Plant Science, Jilin University, Changchun 130062, China.
  • Yu YL; College of Plant Science, Jilin University, Changchun 130062, China.
  • Xi JH; College of Plant Science, Jilin University, Changchun 130062, China.
  • Zhang DW; College of Plant Science, Jilin University, Changchun 130062, China.
Molecules ; 28(12)2023 Jun 19.
Article in En | MEDLINE | ID: mdl-37375399
Imidazole-based compounds are a series of heterocyclic compounds that exhibit a wide range of biological and pharmaceutical activities. However, those extant syntheses using conventional protocols can be time-costly, require harsh conditions, and result in low yields. As a novel and green technique, sonochemistry has emerged as a promising method for organic synthesis with several advantages over conventional methods, including enhancing reaction rates, improving yields, and reducing the use of hazardous solvents. Contemporarily, a growing body of ultrasound-assisted reactions have been applied in the preparation of imidazole derivatives, which demonstrated greater benefits and provided a new strategy. Herein, we introduce the brief history of sonochemistry and focus on the discussion of the multifarious approaches for the synthesis of imidazole-based compounds under ultrasonic irradiation and its advantages in comparison with conventional protocols, including typical name-reactions and various sorts of catalysts in those reactions.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2023 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2023 Document type: Article Affiliation country: Country of publication: