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Metabolic activation and cytotoxicity of metaxalone mediated by cytochrome P450 enzymes and sulfotransferases.
Liu, He; Hu, Zixia; Han, Ningning; Yang, Yi; Zhao, Guode; Su, Mengdie; Zhang, Yue; Li, Weiwei; Peng, Ying; Zheng, Jiang.
Affiliation
  • Liu H; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, PR China.
  • Hu Z; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, PR China.
  • Han N; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, PR China.
  • Yang Y; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, PR China.
  • Zhao G; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, PR China.
  • Su M; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, PR China.
  • Zhang Y; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, PR China.
  • Li W; State Key Laboratory of Functions and Applications of Medicinal Plants, Key Laboratory of Pharmaceutics of Guizhou Province, Guizhou Medical University, Guiyang, Guizhou, 550025, PR China. Electronic address: weiweili0615@163.com.
  • Peng Y; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, PR China. Electronic address: yingpeng1999@163.com.
  • Zheng J; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, PR China; State Key Laboratory of Functions and Applications of Medicinal Plants, Key Laboratory of Pharmaceutics of Guizhou Province, Guizhou Medical University, Guiyang, Guizhou, 550025, PR China. Electroni
Chem Biol Interact ; 382: 110628, 2023 Sep 01.
Article in En | MEDLINE | ID: mdl-37442290
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfotransferases / Cytochrome P-450 Enzyme System Limits: Animals Language: En Journal: Chem Biol Interact Year: 2023 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfotransferases / Cytochrome P-450 Enzyme System Limits: Animals Language: En Journal: Chem Biol Interact Year: 2023 Document type: Article Country of publication: