[A Case of Advanced Esophagogastric Junction Adenocarcinoma with Enlarged Lymph Node Metastases of the Middle Mediastinum and Intraperitoneal That Exhibited pCR by Preoperative SOX Therapy].
Gan To Kagaku Ryoho
; 50(8): 909-912, 2023 Aug.
Article
in Ja
| MEDLINE
| ID: mdl-37608419
ABSTRACT
A 79-year-old man was diagnosed with esophagogastric junction adenocarcinoma, cT3N3M0, cStage â
¢, including enlarged lymph node metastases(Bulky N)in the middle mediastinum and intraperitoneal. A total of 2 cycles of S-1 plus oxaliplatin(SOX)was administered. After neoadjuvant chemotherapy, the primary tumor and enlarged lymph nodes had greatly decreased in size. Subsequently, thoracoscopic subtotal esophagectomy and reconstruction with a gastric tube were performed. Histopathological examinations showed no residual cancer cells in the primary lesion and dissected lymph nodes (pathological complete response). Preoperative chemotherapy containing SOX could be a useful treatment strategy for patients with esophagogastric junction adenocarcinoma with enlarged lymph node metastasis.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Adenocarcinoma
/
Lymphadenopathy
Limits:
Aged
/
Humans
/
Male
Language:
Ja
Journal:
Gan To Kagaku Ryoho
Year:
2023
Document type:
Article