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Clinical characterization, physical frailty, and depression in elderly patients with psoriasis from a reference center in Brazil: a cross-sectional study.
Brandão, Giovana Viotto Cagnon; Pereira, Elizandra Gomes; Haddad, Gabriela Roncada; Miot, Luciane Donida Bartoli; Marques, Silvio Alencar; Miot, Hélio Amante.
Affiliation
  • Brandão GVC; Departamento de Infectologia, Dermatologia, Diagnóstico por Imagem e Radioterapia, Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brasil.
  • Pereira EG; Departamento de Infectologia, Dermatologia, Diagnóstico por Imagem e Radioterapia, Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brasil.
  • Haddad GR; Departamento de Infectologia, Dermatologia, Diagnóstico por Imagem e Radioterapia, Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brasil.
  • Miot LDB; Departamento de Infectologia, Dermatologia, Diagnóstico por Imagem e Radioterapia, Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brasil.
  • Marques SA; Departamento de Infectologia, Dermatologia, Diagnóstico por Imagem e Radioterapia, Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brasil.
  • Miot HA; Departamento de Infectologia, Dermatologia, Diagnóstico por Imagem e Radioterapia, Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brasil. Electronic address: heliomiot@gmail.com.
An Bras Dermatol ; 99(1): 19-26, 2024.
Article in En | MEDLINE | ID: mdl-37612180
BACKGROUND: There are few studies dedicated to the characterization of the geriatric population with psoriasis, which has particularities in terms of clinical manifestations and therapeutic limitations. As psoriasis is a chronic disease, presenting a higher prevalence with age, the increase in life expectancy in Brazil demands knowledge about the behavior of the disease among the elderly. OBJECTIVES: To characterize elderly people with psoriasis from a tertiary service, from the clinical-epidemiological point of view, presence of comorbidities, physical frailty, and affective impact, and to compare these aspects with adults with psoriasis and elderly people without the disease. METHODS: Cross-sectional study of 64 elderly patients with psoriasis, 64 adults with psoriasis, and 64 elderly patients without the disease. Clinical-demographic aspects, the Beck depression scale, and Skindex-16 were evaluated. Indicators of physical frailty were evaluated in elderly patients: handgrip, sit-to-stand test, fatigue, and weight loss >5%. RESULTS: In the elderly, the mean age (SD) of psoriasis onset was 44 (10) years, men represented 47% of the sample, the prevalence of arthritis was 22%, and ungual involvement occurred in 72%. Topical corticosteroids were used more often among elderly people with psoriasis (100%) than among adults with the disease (86%), with no difference among other systemic treatments. Diabetes mellitus occurred in 30% of the elderly. Hypertension (59%), dyslipidemia (52%), depression (34%), and fatigue (59%) were more prevalent among the elderly with psoriasis than among the healthy controls. STUDY LIMITATIONS: The study was carried out in a public reference service for patients with psoriasis, all of which were undergoing treatment. CONCLUSIONS: Elderly people with psoriasis from a tertiary service showed greater affective impairment, metabolic comorbidities, and physical frailty than elderly controls.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Frailty Type of study: Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Adult / Aged / Humans / Male Country/Region as subject: America do sul / Brasil Language: En Journal: An Bras Dermatol Year: 2024 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Frailty Type of study: Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Adult / Aged / Humans / Male Country/Region as subject: America do sul / Brasil Language: En Journal: An Bras Dermatol Year: 2024 Document type: Article Affiliation country: Country of publication: