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Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases.
Nutma, Erik; Fancy, Nurun; Weinert, Maria; Tsartsalis, Stergios; Marzin, Manuel C; Muirhead, Robert C J; Falk, Irene; Breur, Marjolein; de Bruin, Joy; Hollaus, David; Pieterman, Robin; Anink, Jasper; Story, David; Chandran, Siddharthan; Tang, Jiabin; Trolese, Maria C; Saito, Takashi; Saido, Takaomi C; Wiltshire, Katharine H; Beltran-Lobo, Paula; Phillips, Alexandra; Antel, Jack; Healy, Luke; Dorion, Marie-France; Galloway, Dylan A; Benoit, Rochelle Y; Amossé, Quentin; Ceyzériat, Kelly; Badina, Aurélien M; Kövari, Enikö; Bendotti, Caterina; Aronica, Eleonora; Radulescu, Carola I; Wong, Jia Hui; Barron, Anna M; Smith, Amy M; Barnes, Samuel J; Hampton, David W; van der Valk, Paul; Jacobson, Steven; Howell, Owain W; Baker, David; Kipp, Markus; Kaddatz, Hannes; Tournier, Benjamin B; Millet, Philippe; Matthews, Paul M; Moore, Craig S; Amor, Sandra; Owen, David R.
Affiliation
  • Nutma E; Department of Pathology, Amsterdam UMC - Location VUmc, Amsterdam, The Netherlands.
  • Fancy N; Department of Neurobiology and Aging, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
  • Weinert M; Department of Brain Sciences, Imperial College London, London, UK.
  • Tsartsalis S; UK Dementia Research Institute at Imperial College London, London, UK.
  • Marzin MC; Department of Brain Sciences, Imperial College London, London, UK.
  • Muirhead RCJ; Department of Brain Sciences, Imperial College London, London, UK.
  • Falk I; UK Dementia Research Institute at Imperial College London, London, UK.
  • Breur M; Department of Psychiatry, University of Geneva, Geneva, Switzerland.
  • de Bruin J; Department of Pathology, Amsterdam UMC - Location VUmc, Amsterdam, The Netherlands.
  • Hollaus D; Department of Brain Sciences, Imperial College London, London, UK.
  • Pieterman R; UK Dementia Research Institute at Imperial College London, London, UK.
  • Anink J; Viral Immunology Section, NIH, Bethesda, MD, USA.
  • Story D; Flow and Imaging Cytometry Core Facility, NIH, Bethesda, MD, USA.
  • Chandran S; Department of Pathology, Amsterdam UMC - Location VUmc, Amsterdam, The Netherlands.
  • Tang J; Department of Pathology, Amsterdam UMC - Location VUmc, Amsterdam, The Netherlands.
  • Trolese MC; Department of Pathology, Amsterdam UMC - Location VUmc, Amsterdam, The Netherlands.
  • Saito T; Department of Pathology, Amsterdam UMC - Location VUmc, Amsterdam, The Netherlands.
  • Saido TC; Department of (Neuro)Pathology, Amsterdam UMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands.
  • Wiltshire KH; UK Dementia Research Institute at Edinburgh, Edinburgh, UK.
  • Beltran-Lobo P; UK Dementia Research Institute at Edinburgh, Edinburgh, UK.
  • Phillips A; Department of Brain Sciences, Imperial College London, London, UK.
  • Antel J; UK Dementia Research Institute at Imperial College London, London, UK.
  • Healy L; Department of Neuroscience, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy.
  • Dorion MF; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako-shi, Saitama, Japan.
  • Galloway DA; Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University, Nagoya, Japan.
  • Benoit RY; Department of Brain Sciences, Imperial College London, London, UK.
  • Amossé Q; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Ceyzériat K; Department of Brain Sciences, Imperial College London, London, UK.
  • Badina AM; UK Dementia Research Institute at Imperial College London, London, UK.
  • Kövari E; Montreal Neurological Institute, McGill University, Montreal, Canada.
  • Bendotti C; Montreal Neurological Institute, McGill University, Montreal, Canada.
  • Aronica E; Division of Biomedical Sciences, Memorial University of Newfoundland, St. John's, Canada.
  • Radulescu CI; Division of Biomedical Sciences, Memorial University of Newfoundland, St. John's, Canada.
  • Wong JH; Division of Biomedical Sciences, Memorial University of Newfoundland, St. John's, Canada.
  • Barron AM; Department of Psychiatry, University of Geneva, Geneva, Switzerland.
  • Smith AM; Department of Psychiatry, University of Geneva, Geneva, Switzerland.
  • Barnes SJ; Department of Psychiatry, University of Geneva, Geneva, Switzerland.
  • Hampton DW; Department of Psychiatry, University of Geneva, Geneva, Switzerland.
  • van der Valk P; Department of Neuroscience, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy.
  • Jacobson S; Department of (Neuro)Pathology, Amsterdam UMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands.
  • Howell OW; Department of Brain Sciences, Imperial College London, London, UK.
  • Baker D; UK Dementia Research Institute at Imperial College London, London, UK.
  • Kipp M; Neurobiology of Aging and Disease Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore.
  • Kaddatz H; Neurobiology of Aging and Disease Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore.
  • Tournier BB; UK Dementia Research Institute at Imperial College London, London, UK.
  • Millet P; Centre for Brain Research and Department of Pharmacology and Clinical Pharmacology, University of Auckland, Auckland, New Zealand.
  • Matthews PM; Department of Brain Sciences, Imperial College London, London, UK.
  • Moore CS; UK Dementia Research Institute at Imperial College London, London, UK.
  • Amor S; UK Dementia Research Institute at Edinburgh, Edinburgh, UK.
  • Owen DR; Department of Pathology, Amsterdam UMC - Location VUmc, Amsterdam, The Netherlands.
Nat Commun ; 14(1): 5247, 2023 08 28.
Article in En | MEDLINE | ID: mdl-37640701

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / Neurodegenerative Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / Neurodegenerative Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Country of publication: