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Neonatal AKI: An update.
Hu, J; Ananth, D; Sethi, S K; Taliwal, N; Govindan, S; Raina, R.
Affiliation
  • Hu J; Department of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA.
  • Ananth D; Department of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA.
  • Sethi SK; Pediatric Nephrology & Pediatric Kidney Transplantation, Kidney and Urology Institute, Medanta, The Medicity Hospital, Gurgaon, India.
  • Taliwal N; Akron Nephrology Associates/Cleveland Clinic Akron General Medical Center, Akron, OH, USA.
  • Govindan S; Department of Pediatric Nephrology, Dr. Mehta's Hospitals, Chetpet and Vellapanchavadi, Chennai, India.
  • Raina R; Akron Nephrology Associates/Cleveland Clinic Akron General Medical Center, Akron, OH, USA.
J Neonatal Perinatal Med ; 16(3): 361-373, 2023.
Article in En | MEDLINE | ID: mdl-37718869
ABSTRACT
Neonatal acute kidney injury (AKI) is a common complication, especially in the neonatal intensive care unit, that is associated with long term consequences and poor outcomes. Early detection and treatment is critical. Currently, neonatal AKI is defined with urinary markers and serum creatinine, with limitations on early detection and individual treatment. There have been numerous biomarkers and risk factor scores that have been studied for their ability to predict neonatal AKI. To move towards personalized medicine, neonatal AKI must be categorized into phenotypes and subphenotypes that fully encapsulate the diverse causes and specific treatments. This review aims to advance our understanding of neonatal AKI detection through the use of biomarkers, subphenotypes, and phenotypes to move towards personalized treatment strategies.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies / Screening_studies Language: En Journal: J Neonatal Perinatal Med Year: 2023 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies / Screening_studies Language: En Journal: J Neonatal Perinatal Med Year: 2023 Document type: Article Affiliation country: