Effect of 3% Diquafosol Sodium on Dry Eye After Femtosecond Laser-Assisted In Situ Keratomileusis and Small Incision Lenticule Extraction Surgery in High-Myopic Eyes.
Eye Contact Lens
; 49(11): 489-497, 2023 Nov 01.
Article
in En
| MEDLINE
| ID: mdl-37729174
ABSTRACT
PURPOSE:
To evaluate the effect of 3% diquafosol sodium eye drop on dry eye after femtosecond laser-assisted in situ keratomileusis (FS-LASIK) and small incision lenticule extraction (SMILE) in high-myopic eyes.METHODS:
Eighty-one cases with high myopia (162 eyes) who received FS-LASIK or SMILE were divided into four groups by surgical design and tear film stability D-FS-LASIK (5sRESULTS:
The D-SMILE group showed increase in BUT postoperatively (1m P =0.006, 3m P =0.004), whereas C-FS-LASIK (1m P =0.012) and C-SMILE (1m P =0.036) groups showed decrease in BUT. Higher ΔBUT were observed in D-FS-LASIK (1m P =0.027) and D-SMILE (1m P =0.001, 3m P =0.012) postoperatively. The D-FS-LASIK group showed less decrease than C-FS-LASIK group in Schirmer I. The D-SMILE group showed increase in Schirmer I, whereas C-SMILE showed decrease in 3 months. ΔOSDI was lower in D-SMILE group than in C-SMILE group (1m P =0.026, 3m P =0.035). Fatigue was severer in D-SMILE group than in C-SMILE group preoperatively ( P =0.019), although there was no significant difference postoperatively. Objective scattering index (1m P =0.002, 3m P =0.021) and tear film objective scattering index (1m P =0.005, 3m P =0.010) were lower in D-FS-LASIK group than in C-FS-LASIK group postoperatively. The D-FS-LASIK group showed better VA20% ( P =0.036) and VA9% ( P =0.027) than the C-FS-LASIK group 1 month postoperatively.CONCLUSIONS:
3% Diquafosol sodium eye drop was effective for SMILE and FS-LASIK-related dry eye in high-myopic eyes. It is necessary to focus on perioperative anti-dry eye management and especially pay attention to the eyes with risk factors, including unstable tear film, high myopia, and FS-LASIK surgery.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dry Eye Syndromes
/
Keratomileusis, Laser In Situ
/
Myopia
Type of study:
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Eye Contact Lens
Journal subject:
OFTALMOLOGIA
Year:
2023
Document type:
Article
Affiliation country: