Your browser doesn't support javascript.
loading
Linking donor-specific antibody generation with natural killer cells in antibody-mediated kidney graft rejection.
Perkins, Griffith B; Fairchild, Robert L.
Affiliation
  • Perkins GB; Central and Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital, Adelaide, South Australia, Australia; Adelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia; Immunology Directorate, SA Pathology, Adelaide, South Australia, Australia. Electronic address: griffith.perkins@adelaide.edu.au.
  • Fairchild RL; Department of Inflammation and Immunity, Cleveland Clinic, Cleveland, Ohio, USA; Transplant Center, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address: fairchr@ccf.org.
Kidney Int ; 104(4): 644-646, 2023 10.
Article in En | MEDLINE | ID: mdl-37739612
Natural killer (NK) cell infiltration of kidney allografts is a distinguishing feature of antibody-mediated rejection. Bailly et al. identify a distinct population of cytotoxic CD160+ interleukin-21 receptor+ CD56dimCD16bright NK cells that are uniquely found in the peripheral blood of donor-specific antibody-positive kidney transplant recipients and are present in kidney allografts with active antibody-mediated rejection. This population is implicated in a T follicular helper/interleukin-21/NK cell axis that links donor-specific antibody generation with graft-infiltrating NK cells in antibody-mediated rejection.
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Graft Rejection / Antibodies Limits: Humans Language: En Journal: Kidney Int Year: 2023 Document type: Article Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Graft Rejection / Antibodies Limits: Humans Language: En Journal: Kidney Int Year: 2023 Document type: Article Country of publication: