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Microbial production and applications of ß-glucosidase-A review.
Yang, Wenqi; Su, Yaowu; Wang, Rubing; Zhang, Huanyu; Jing, Hongyan; Meng, Jie; Zhang, Guoqi; Huang, Luqi; Guo, Lanping; Wang, Juan; Gao, Wenyuan.
Affiliation
  • Yang W; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China; Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin 300072, China.
  • Su Y; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China; Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin 300072, China.
  • Wang R; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China; Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin 300072, China.
  • Zhang H; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China; Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin 300072, China.
  • Jing H; Traditional Chinese Medicine College, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
  • Meng J; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China; Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin 300072, China.
  • Zhang G; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China; Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin 300072, China.
  • Huang L; National Resource Center for Chinese Meteria Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
  • Guo L; National Resource Center for Chinese Meteria Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs. Electronic address: glp01@126.com.
  • Wang J; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China; Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin 300072, China. Electronic address: drwangjuan@tju.edu.cn.
  • Gao W; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China; Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin 300072, China. Electronic address: pharmgao@tju.edu.cn.
Int J Biol Macromol ; 256(Pt 2): 127915, 2024 Jan.
Article in En | MEDLINE | ID: mdl-37939774
ß-Glucosidase exists in all areas of living organisms, and microbial ß-glucosidase has become the main source of its production because of its unique physicochemical properties and the advantages of high-yield production by fermentation. With the rise of the green circular economy, the production of enzymes through the fermentation of waste as the substrate has become a popular trend. Lignocellulosic biomass is an easily accessible and sustainable feedstock that exists in nature, and the production of biofuels from lignocellulosic biomass requires the involvement of ß-glucosidase. This review proposes ways to improve ß-glucosidase yield and catalytic efficiency. Optimization of growth conditions and purification strategies of enzymes can increase enzyme yield, and enzyme immobilization, genetic engineering, protein engineering, and whole-cell catalysis provide solutions to enhance the catalytic efficiency and activity of ß-glucosidase. Besides, the diversified industrial applications, challenges and prospects of ß-glucosidase are also described.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Beta-Glucosidase / Lignin Language: En Journal: Int J Biol Macromol Year: 2024 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Beta-Glucosidase / Lignin Language: En Journal: Int J Biol Macromol Year: 2024 Document type: Article Affiliation country: Country of publication: