Mediterranean diet and colorectal adenomas: a systematic review and meta-analysis of observational studies.
Eur J Cancer Prev
; 33(3): 223-231, 2024 May 01.
Article
in En
| MEDLINE
| ID: mdl-37942952
ABSTRACT
Colorectal adenomas (CRAs) are epithelial lesions of the large bowel that can develop into colorectal cancer. Some studies have shown an inverse association of the Mediterranean diet (MED) with adenoma, but the extent of the association is equivocal. Owing to the lack of meta-analytical evidence in the literature, we sought to assess the association between MED and CRAs by conducting a systematic review and meta-analysis. A comprehensive systematic literature search of observational studies was conducted via PubMed, Scopus, Google Scholar and Web of Sciences up to May 2023. Studies were included in our review if they evaluated the association between MED and CRA, following an observational study design. Six studies were included in this study. We found that adherence to MED was inversely associated with CRA risk (odds ratio, 0.79; confidence interval, 0.73-0.85); implying that higher adherence to MED could reduce the risk of CRA by ~21%. Stratification by the year of studies, sex, study design, country and exposure showed a significant association between MED and CRA. The results of the current study provide evidence of an inverse association between adherence to MED and CRAs.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Colorectal Neoplasms
/
Adenoma
/
Diet, Mediterranean
Type of study:
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Eur J Cancer Prev
Journal subject:
NEOPLASIAS
/
SAUDE PUBLICA
Year:
2024
Document type:
Article
Affiliation country: