Classic Hodgkin Lymphoma in Adolescents and Young Adults.
J Clin Oncol
; 42(6): 653-664, 2024 Feb 20.
Article
in En
| MEDLINE
| ID: mdl-37983570
ABSTRACT
Hodgkin lymphoma (HL) represents one of the more common cancers occurring in adolescent and young adults (AYAs) age 15-39 years. Despite a generally high cure rate, age-related differences in HL biology and the optimal therapeutic approaches including supportive care and risks for long-term adverse effects in the AYA population remain understudied. After an overview of HL epidemiology and biology in the AYA population, this review will cover frontline pediatric and adult treatment approaches. Recently completed and ongoing studies will foster harmonization of risk group definition and trial eligibility criteria across the AYA spectrum, enabling more rapid progress. In addition to treatment approaches, an evolving holistic care approach to AYA HL will result in enhanced understanding of unique challenges, and continued improved short- and long-term outcome for these patients.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hodgkin Disease
Limits:
Adolescent
/
Adult
/
Child
/
Humans
Language:
En
Journal:
J Clin Oncol
Year:
2024
Document type:
Article