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Signaling via a CD28/CD40 chimeric costimulatory antigen receptor (CoStAR™), targeting folate receptor alpha, enhances T cell activity and augments tumor reactivity of tumor infiltrating lymphocytes.
Kalaitsidou, Milena; Moon, Owen R; Sykorova, Martina; Bao, Leyuan; Qu, Yun; Sukumaran, Sujita; Valentine, Michael; Zhou, Xingliang; Pandey, Veethika; Foos, Kay; Medvedev, Sergey; Powell, Daniel J; Udyavar, Akshata; Gschweng, Eric; Rodriguez, Ruben; Dudley, Mark E; Hawkins, Robert E; Kueberuwa, Gray; Bridgeman, John S.
Affiliation
  • Kalaitsidou M; Department of Research, Instil Bio, Dallas, TX, United States.
  • Moon OR; Department of Research, Instil Bio, Dallas, TX, United States.
  • Sykorova M; Department of Research, Instil Bio, Dallas, TX, United States.
  • Bao L; Department of Research, Instil Bio, Dallas, TX, United States.
  • Qu Y; Department of Research, Instil Bio, Dallas, TX, United States.
  • Sukumaran S; Department of Research, Instil Bio, Dallas, TX, United States.
  • Valentine M; Department of Research, Instil Bio, Dallas, TX, United States.
  • Zhou X; Department of Research, Instil Bio, Dallas, TX, United States.
  • Pandey V; Ovarian Cancer Research Center, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
  • Foos K; Ovarian Cancer Research Center, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
  • Medvedev S; Ovarian Cancer Research Center, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
  • Powell DJ; Ovarian Cancer Research Center, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
  • Udyavar A; Department of Research, Instil Bio, Dallas, TX, United States.
  • Gschweng E; Department of Research, Instil Bio, Dallas, TX, United States.
  • Rodriguez R; Department of Research, Instil Bio, Dallas, TX, United States.
  • Dudley ME; Department of Research, Instil Bio, Dallas, TX, United States.
  • Hawkins RE; Department of Research, Instil Bio, Dallas, TX, United States.
  • Kueberuwa G; Department of Research, Instil Bio, Dallas, TX, United States.
  • Bridgeman JS; Department of Research, Instil Bio, Dallas, TX, United States.
Front Immunol ; 14: 1256491, 2023.
Article in En | MEDLINE | ID: mdl-38022678
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Chimeric Antigen / Melanoma Limits: Humans Language: En Journal: Front Immunol Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Chimeric Antigen / Melanoma Limits: Humans Language: En Journal: Front Immunol Year: 2023 Document type: Article Affiliation country: Country of publication: