Functional gallbladder disorder: Interim analysis of a prospective cohort study.
Am J Surg
; 229: 129-132, 2024 Mar.
Article
in En
| MEDLINE
| ID: mdl-38110322
ABSTRACT
BACKGROUND:
Functional gallbladder disorder (FGBD) remains a controversial indication for cholecystectomy.METHODS:
A prospective cohort study enrolled patients strictly meeting Rome criteria for FGBD, and cholecystectomy was performed. They were assessed pre- and 3 and 6 months postoperatively with surveys of abdominal pain and quality of life (RAPID and SF-12 surveys, respectively). Interim analysis was performed.RESULTS:
Although neither ejection fraction nor pain reproduction predicted success after cholecystectomy, the vast majority of enrolled patients had a successful outcome after undergoing cholecystectomy for FGBD of a planned 100 patients, 46 were enrolled. Of 31 evaluable patients, 26 (83.9 â%) reported RAPID improvement and 28 (93.3 â%) SF12 improvement at 3- or 6-month follow-up.CONCLUSION:
FGBD, strictly diagnosed, should perhaps no longer be a controversial indication for cholecystectomy, since its success rate for biliary pain in this study was similar to that for symptomatic cholelithiasis. Larger-scale studies or randomized trials may confirm these findings.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biliary Dyskinesia
/
Gallbladder Diseases
Limits:
Humans
Language:
En
Journal:
Am J Surg
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: