Influence of anxiety/depression on chemotherapy-induced oral mucositis and related quality of life: A prospective cohort study.
J Psychosom Res
; 177: 111577, 2024 02.
Article
in En
| MEDLINE
| ID: mdl-38154442
ABSTRACT
OBJECTIVE:
The impact of anxiety and depression on chemotherapy-induced oral mucositis has not been extensively explored in the literature. The aim of the present study was to evaluate anxiety/depressive symptoms, health-related quality of life, and oral health-related quality of life and their association with oral mucositis among individuals receiving chemotherapy.METHODS:
This is a prospective longitudinal study carried out at a Brazilian referral service. The Hospital Anxiety and Depression Scale (HADS), World Health Organization Quality of Life-BREF (WHOQOL-BREF), and Oral Health Impact Profile questionnaire (OHIP-14) were applied at D0 (before chemotherapy) and D15 of chemotherapy. Clinicodemographic data and oral mucositis severity scores were evaluated.RESULTS:
A total of 37 individuals (median age 49 years) were included in the study. Nearly 38% of patients developed chemotherapy-induced oral mucositis and had higher anxiety/depression scores at baseline. Oral mucositis had a negative impact on oral health-related quality of life regarding functional limitation, physical pain, physical disability, and handicap.CONCLUSION:
Anxiety/depressive symptoms are associated with oral mucositis that affects overall health and oral health-related quality of life.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Stomatitis
/
Antineoplastic Agents
Limits:
Humans
/
Middle aged
Language:
En
Journal:
J Psychosom Res
/
J. psychosom. res
/
Journal of psychosomatic research
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: