Resistance to Chlorhexidine and Benzalkonium Chloride in E. Coli ST131, A. Baumannii, and P. Aeruginosa Isolates.
Clin Lab
; 70(1)2024 Jan 01.
Article
in En
| MEDLINE
| ID: mdl-38213201
ABSTRACT
BACKGROUND:
The goal was to assess the antimicrobial efficacy of two commonly used biocides, chlorhexidine, and benzalkonium chloride, against MDR isolates of Pseudomonas aeruginosa, Acinetobacter baumannii, and Escherichia coli ST131, as well as the prevalence of resistance genes.METHODS:
MIC of chlorhexidine and benzalkonium chloride and their effects on both the planktonic phase and biofilm were determined. Finally, the presence of genes responsible for resistance to quaternary ammonium compounds was investigated by PCR.RESULTS:
No significant relationship was observed between the presence of resistance genes and different concentrations of quaternary ammonium compounds (benzalkonium chloride). There was no association between biofilm formation and the presence of resistance genes.CONCLUSIONS:
Chlorhexidine digluconate and benzalkonium chloride at appropriate concentrations could prevent biofilm formation.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Benzalkonium Compounds
/
Chlorhexidine
Type of study:
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Clin Lab
/
Clin. lab
/
Clinical laboratory
Journal subject:
TECNICAS E PROCEDIMENTOS DE LABORATORIO
Year:
2024
Document type:
Article
Country of publication: