18S rRNA sequencing and homology analysis of post-traumatic bloodstream infection with Saprochaete clavata (Magnusiomyces clavatus) and a case report.
New Microbiol
; 46(4): 400-406, 2024 Jan.
Article
in En
| MEDLINE
| ID: mdl-38252052
ABSTRACT
We present a case of bloodstream infection with Saprochaete clavata following an abdominal steel impact injury in a 52-year-old man, whose non-healing abdominal wound was also highly suspected of being caused by Saprochaete clavata. Saprochaete clavata is a very uncommon fungal pathogen. Our case is distinctive in that previous reports have typically involved immunocompromised, malignant, or leukemic patients. In contrast, our case involved a middle-aged man in good health who had ileal perforation repair for gastrointestinal perforation. Post-surgery, Saprochaete clavata was isolated from the incision exudate and blood samples. The pathogen was characterized and the drug sensitivity test was performed, and based on their results a clinical treatment plan was devised. The combination antifungal treatment comprising voriconazole and caspofungin significantly controlled the patient's infection and gradually healed the wound. Therefore, early isolation and characterization are essential because invasive fungal diseases have a high death rate.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sepsis
/
Saccharomycetales
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
New Microbiol
Journal subject:
MICROBIOLOGIA
Year:
2024
Document type:
Article
Affiliation country: