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A clinical microscopy dataset to develop a deep learning diagnostic test for urinary tract infection.
Liou, Natasha; De, Trina; Urbanski, Adrian; Chieng, Catherine; Kong, Qingyang; David, Anna L; Khasriya, Rajvinder; Yakimovich, Artur; Horsley, Harry.
Affiliation
  • Liou N; Bladder Infection and Immunity Group (BIIG), UCL Centre for Kidney & Bladder Health, Division of Medicine, University College London, Royal Free Hospital Campus, London, UK.
  • De T; UCL EGA Institute for Women's Health, Faculty of Population Health Sciences, University College London, London, UK.
  • Urbanski A; Center for Advanced Systems Understanding (CASUS), Görlitz, Germany.
  • Chieng C; Helmholtz-Zentrum Dresden-Rossendorf e. V. (HZDR), Dresden, Germany.
  • Kong Q; Center for Advanced Systems Understanding (CASUS), Görlitz, Germany.
  • David AL; Helmholtz-Zentrum Dresden-Rossendorf e. V. (HZDR), Dresden, Germany.
  • Khasriya R; Bladder Infection and Immunity Group (BIIG), UCL Centre for Kidney & Bladder Health, Division of Medicine, University College London, Royal Free Hospital Campus, London, UK.
  • Yakimovich A; Bladder Infection and Immunity Group (BIIG), UCL Centre for Kidney & Bladder Health, Division of Medicine, University College London, Royal Free Hospital Campus, London, UK.
  • Horsley H; UCL EGA Institute for Women's Health, Faculty of Population Health Sciences, University College London, London, UK.
Sci Data ; 11(1): 155, 2024 Feb 01.
Article in En | MEDLINE | ID: mdl-38302487
ABSTRACT
Urinary tract infection (UTI) is a common disorder. Its diagnosis can be made by microscopic examination of voided urine for markers of infection. This manual technique is technically difficult, time-consuming and prone to inter-observer errors. The application of computer vision to this domain has been slow due to the lack of a clinical image dataset from UTI patients. We present an open dataset containing 300 images and 3,562 manually annotated urinary cells labelled into seven classes of clinically significant cell types. It is an enriched dataset acquired from the unstained and untreated urine of patients with symptomatic UTI using a simple imaging system. We demonstrate that this dataset can be used to train a Patch U-Net, a novel deep learning architecture with a random patch generator to recognise urinary cells. Our hope is, with this dataset, UTI diagnosis will be made possible in nearly all clinical settings by using a simple imaging system which leverages advanced machine learning techniques.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Tract Infections / Deep Learning Type of study: Diagnostic_studies / Guideline Limits: Humans Language: En Journal: Sci Data Year: 2024 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Tract Infections / Deep Learning Type of study: Diagnostic_studies / Guideline Limits: Humans Language: En Journal: Sci Data Year: 2024 Document type: Article Affiliation country: