HCV Reactivation in a Patient with Hepatocellular Carcinoma Due to Sorafenib: A Case Report.
Int Med Case Rep J
; 17: 121-124, 2024.
Article
in En
| MEDLINE
| ID: mdl-38370606
ABSTRACT
The global prevalence of hepatitis C virus (HCV) infection is approximately 3%, with a post-infection chronicity rate of up to 50%-85%. HCV reactivation can occur when anti-HCV positive individuals receive antineoplastic therapy. In this study, we report a case of an anti-HCV positive patient with negative HCV RNA after 12 weeks of direct antiviral therapy. Two months later, sorafenib was used to treat hepatocellular carcinoma, and HCV reactivation occurred after 8 months of the treatment. HCV RNA was negative after 12 weeks of antiviral treatment with Sofosbuvir-velpatasvir. We also discussed the mechanism of HCV reactivation caused by sorafenib and the antiviral treatment regimen after HCV reactivation with the relevant literature.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Int Med Case Rep J
Year:
2024
Document type:
Article