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Total Laryngectomy for Respiratory Complications From Advanced Duchenne Muscular Dystrophy.
Peleman, John; Lin, Jared S; Lin, Ho-Sheng.
Affiliation
  • Peleman J; Department of Otolaryngology-Head and Neck Surgery, Wayne State University, Detroit, Michigan, U.S.A.
  • Lin JS; Departement of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, U.S.A.
  • Lin HS; Department of Otolaryngology-Head and Neck Surgery, Wayne State University, Detroit, Michigan, U.S.A.
Laryngoscope ; 134(8): 3677-3678, 2024 Aug.
Article in En | MEDLINE | ID: mdl-38400802
ABSTRACT
Due to respiratory weakness, late-stage Duchenne muscular dystrophy (DMD) patients may suffer from chronic aspiration, which is sometimes treated using tracheostomy. However, definitive laryngectomy has not been described in the literature as an aspiration prevention modality in DMD, especially in patients with contraindications to tracheostomy. A case is presented for a patient with advanced stage Duchenne muscular dystrophy suffering from chronic aspiration pneumonia and excessive oral secretions who became ventilator dependent. A tracheostomy was placed, but was noted to have excessive secretions and high cuff pressures, which have been known to be associated with worsened swallow dysfunction as well as tracheoinnominate fistula. The patient therefore was considered for total laryngectomy, which he underwent successfully. Post-operatively, the patient was noted to have improved subjective quality of life, engaged in an oral diet, and had less secretions surrounding his tracheostoma post-operatively. Aspiration prevention surgeries are done to improve quality of life by improving oral intake, decreasing the need for frequent suctioning, and can sometimes allow for speech. It is important to consider quality of life for DMD patients as more of these patients are living into their 30s with the aid of mechanical ventilation. Laryngectomy is a surgery that can definitively correct chronic aspiration while allowing for oral intake. Laryngoscope, 1343677-3678, 2024.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Muscular Dystrophy, Duchenne / Laryngectomy Limits: Adult / Humans / Male Language: En Journal: Laryngoscope Journal subject: OTORRINOLARINGOLOGIA Year: 2024 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Muscular Dystrophy, Duchenne / Laryngectomy Limits: Adult / Humans / Male Language: En Journal: Laryngoscope Journal subject: OTORRINOLARINGOLOGIA Year: 2024 Document type: Article Affiliation country: