Endothelial lipid droplets drive atherosclerosis and arterial hypertension.
Trends Endocrinol Metab
; 35(6): 453-455, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38431437
ABSTRACT
Lipid droplets (LDs) are essential for cellular pathophysiology. In two recent reports, Kim et al. and Boutagy et al. show that accumulation of LDs in endothelial cells (ECs) elevates blood pressure and accelerates progression of atherosclerosis. These findings identify a novel mechanism of EC lipid metabolism which drives cardiometabolic diseases.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Endothelial Cells
/
Atherosclerosis
/
Lipid Droplets
/
Hypertension
Limits:
Animals
/
Humans
Language:
En
Journal:
Trends Endocrinol Metab
Journal subject:
ENDOCRINOLOGIA
/
METABOLISMO
Year:
2024
Document type:
Article