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Features of immune reactivity of the spleen and mechanisms of organ damage under the influence of animal venom toxins including scorpions (review).
Samborska, Inha; Maievskyi, Oleksandr; Podzihun, Larysa; Lavrynenko, Victoriia.
Affiliation
  • Samborska I; NATIONAL PIROGOV MEMORIAL MEDICAL UNIVERSITY, VINNYTSIA, UKRAINE.
  • Maievskyi O; EDUCATIONAL AND SCIENTIFIC CENTER "INSTITUTE OF BIOLOGY AND MEDICINE" OF TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV, KYIV, UKRAINE.
  • Podzihun L; BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
  • Lavrynenko V; EDUCATIONAL AND SCIENTIFIC CENTER "INSTITUTE OF BIOLOGY AND MEDICINE" OF TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV, KYIV, UKRAINE.
Wiad Lek ; 77(1): 120-125, 2024.
Article in En | MEDLINE | ID: mdl-38431816
ABSTRACT

OBJECTIVE:

Aim:

To establish features of immune reactivity of the spleen and mechanisms of organ damage under the influence of animal venom toxins including scorpions. PATIENTS AND

METHODS:

Materials and

Methods:

A thorough literature analysis was conducted on the basis of PubMed, Google Scholar, Web of Science, and Scopus databases. When processing the search results, we chose the newest publications up to 5 years old or the most thorough publications that vividly described the essence of our topic.

CONCLUSION:

Conclusions:

Spleen plays a leading role in the implementation of the body's defense processes, the elimination of structural elements affected by toxins, and the restoration of immune homeostasis. Its participation in the formation of the immune response can be accompanied by qualitative and quantitative changes in histological organization. Morpho-functional changes in the spleen under the action of animal venom toxins currently require careful study, because from the information available in the literature today, it is not possible to clearly construct a complete picture of lesions of certain components of the organ at the microscopic or submicroscopic levels. Therefore, this direction of research in the medical field is currently relevant, taking into account the existence of a large number of poisonous animals, including scorpions.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scorpions / Spleen Limits: Animals Language: En Journal: Wiad Lek Journal subject: MEDICINA Year: 2024 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scorpions / Spleen Limits: Animals Language: En Journal: Wiad Lek Journal subject: MEDICINA Year: 2024 Document type: Article Affiliation country: Country of publication: