Shape-Sensing Robotic-Assisted Bronchoscopy versus Computed Tomography-Guided Transthoracic Biopsy for the Evaluation of Subsolid Pulmonary Nodules.
Respiration
; 103(5): 280-288, 2024.
Article
in En
| MEDLINE
| ID: mdl-38471496
ABSTRACT
INTRODUCTION:
Lung cancer remains the leading cause of cancer death worldwide. Subsolid nodules (SSN), including ground-glass nodules (GGNs) and part-solid nodules (PSNs), are slow-growing but have a higher risk for malignancy. Therefore, timely diagnosis is imperative. Shape-sensing robotic-assisted bronchoscopy (ssRAB) has emerged as reliable diagnostic procedure, but data on SSN and how ssRAB compares to other diagnostic interventions such as CT-guided transthoracic biopsy (CTTB) are scarce. In this study, we compared diagnostic yield of ssRAB versus CTTB for evaluating SSN.METHODS:
A retrospective study of consecutive patients who underwent either ssRAB or CTTB for evaluating GGN and PSN with a solid component less than 6 mm from February 2020 to April 2023 at Mayo Clinic Florida and Rochester. Clinicodemographic information, nodule characteristics, diagnostic yield, and complications were compared between ssRAB and CTTB.RESULTS:
A total of 66 nodules from 65 patients were evaluated 37 PSN and 29 GGN. Median size of PSN solid component was 5 mm (IQR 4.5, 6). Patients were divided into two groups 27 in the ssRAB group and 38 in the CTTB group. Diagnostic yield was 85.7% for ssRAB and 89.5% for CTTB (p = 0.646). Sensitivity for malignancy was similar between ssRAB and CTTB (86.4% vs. 88.5%; p = 0.828), with no statistical difference. Complications were more frequent in CTTB with no significant difference (8 vs. 2; p = 0.135).CONCLUSION:
Diagnostic yield for SSN was similarly high for ssRAB and CTTB, with ssRAB presenting less complications and allowing mediastinal staging within the same procedure.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bronchoscopy
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Tomography, X-Ray Computed
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Multiple Pulmonary Nodules
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Image-Guided Biopsy
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Robotic Surgical Procedures
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Lung Neoplasms
Limits:
Aged
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Female
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Humans
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Male
/
Middle aged
Language:
En
Journal:
Respiration
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: