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Accelerating Drug Development Using Spatial Multi-omics.
Goodwin, Richard J A; Platz, Stefan J; Reis-Filho, Jorge S; Barry, Simon T.
Affiliation
  • Goodwin RJA; Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, United Kingdom.
  • Platz SJ; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, United Kingdom.
  • Reis-Filho JS; Cancer Biomarker Development, Early Oncology, AstraZeneca, Gaithersburg, Maryland.
  • Barry ST; Bioscience, Early Oncology, AstraZeneca, Cambridge, United Kingdom.
Cancer Discov ; 14(4): 620-624, 2024 Apr 04.
Article in En | MEDLINE | ID: mdl-38571424
ABSTRACT

SUMMARY:

Spatial biology approaches enabled by innovations in imaging biomarker platforms and artificial intelligence-enabled data integration and analysis provide an assessment of patient and disease heterogeneity at ever-increasing resolution. The utility of spatial biology data in accelerating drug programs, however, requires balancing exploratory discovery investigations against scalable and clinically applicable spatial biomarker analysis.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Artificial Intelligence / Multiomics Limits: Humans Language: En Journal: Cancer Discov Year: 2024 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Artificial Intelligence / Multiomics Limits: Humans Language: En Journal: Cancer Discov Year: 2024 Document type: Article Affiliation country: Country of publication: