Remission of startle epilepsy provoked by acoustic stimuli following complete callosotomy: A case study.
Epileptic Disord
; 26(4): 510-513, 2024 Aug.
Article
in En
| MEDLINE
| ID: mdl-38713433
ABSTRACT
Herein, we present the case of a 21-year-old man with a history of generalized tonic seizures since the age of 4 years. These seizures occurred either spontaneously or could be provoked by auditory stimuli such as the sounds of a vacuum cleaner or an electric shaver. Despite trials with 10 different anti-seizure medications, his seizures remained refractory. Interictal electroencephalography (EEG) revealed generalized epileptiform activity, whereas ictal EEG showed a generalized attenuation pattern. Magnetic resonance imaging revealed extensive chronic infarctions, predominantly in the bilateral cerebral watershed areas. At the age of 17, the patient underwent a one-stage complete callosotomy, which only achieved remission of auditory-provoked seizures. Based on this experience and published reports, we propose that the posterior corpus callosum, particularly the isthmus and anterior splenium, may be involved in seizures caused by unexpected sound stimuli.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Acoustic Stimulation
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Corpus Callosum
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Epilepsy, Reflex
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Electroencephalography
Limits:
Adult
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Humans
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Male
Language:
En
Journal:
Epileptic Disord
Journal subject:
CEREBRO
/
NEUROLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: