Molecular Pathology of Thyroid Tumors: Old Problems and New Concepts.
Clin Lab Med
; 44(2): 305-324, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38821646
ABSTRACT
The molecular signatures of many thyroid tumors have been uncovered. These discoveries have translated into clinical practice and are changing diagnostic and tumor classification paradigms. Here, the findings of recent studies are presented with special emphasis on how molecular insights are impacting the understating of RAS mutant thyroid nodules, Hürthel cell neoplasms, and unusual thyroid tumors, such as hyalinizing trabecular tumor, secretory carcinoma of the thyroid, and sclerosing mucoepidermoid carcinoma with eosinophilia. In addition, the utility of detecting actionable molecular alterations by immunohistochemistry in advanced and aggressive thyroid cancer is also discussed.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Thyroid Neoplasms
Limits:
Humans
Language:
En
Journal:
Clin Lab Med
Year:
2024
Document type:
Article
Country of publication: