Linguistics-based formalization of the antibody language as a basis for antibody language models.
Nat Comput Sci
; 4(6): 412-422, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38877120
ABSTRACT
Apparent parallels between natural language and antibody sequences have led to a surge in deep language models applied to antibody sequences for predicting cognate antigen recognition. However, a linguistic formal definition of antibody language does not exist, and insight into how antibody language models capture antibody-specific binding features remains largely uninterpretable. Here we describe how a linguistic formalization of the antibody language, by characterizing its tokens and grammar, could address current challenges in antibody language model rule mining.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Linguistics
/
Antibodies
Limits:
Humans
Language:
En
Journal:
Nat Comput Sci
Year:
2024
Document type:
Article
Affiliation country: